Case Center for Synchrotron Biosciences

We are a Research Resource Center funded by the National Institute of Biomedical Imaging and Bioengineering serving an international community of biomedical scientists.

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Welcome

Many of the advances in structural molecular biology and related biosciences are the result of the rapidly occurring developments at synchrotrons. These include X-ray crystallography for protein structure determination, X-ray spectroscopy for examination of metalloprotein structure, and synchrotron footprinting technologies for examining macromolecular structure and dynamics. The Case School of Medicine of Case Western Reserve University established the Case Center for Proteomics and Bioinformatics for expanding the state-of-the art in proteomics research. This center provides administrative oversight for the Case Center for Synchrotron Biosciences (CSB) which is funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) as a Biotechnology Research Resource to serve an international community of biomedical scientists. The CSB is catalyzing further development and application of synchrotron radiation tools through a number of multidisciplinary collaborations and partnerships among an international community of scientists. The research facility located at the National Synchrotron Light Source (NSLS) at the Brookhaven National Laboratory (BNL) in New York. The NSLS, as a Department of Energy funded facility, has as a mission to provide academic institutions access to synchrotron light through various collaboration and consortium arrangements.

CWRU School of Medicine

Since 1843, the Case Western Reserve University School of Medicine has been dedicated to enhancing human health as a leader and innovator in the fields of medical education and biomedical research. Building upon its proud history while embracing today's challenges, the School's mission remains unchanged: to educate future physicians who will care for patients with competence, creativity and compassion, in a setting that fosters collegiality, leadership, and excellence in scholarship and research.

National Synchrotron Light Source

The National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory (BNL) in Upton, New York, is a national user research facility funded by the U.S. Department of Energy (DOE). The NSLS experimental floor consists of two electron storage rings: an X-Ray Ring and a VUV (Vacuum Ultra Violet) Ring which provide intense focused light spanning the electromagnetic spectrum from the infrared through x-rays. The properties of this light and the specially designed experimental stations, called beamlines, allow scientists in many fields of research to perform experiments not otherwise possible at their own laboratories.

National Synchrotron Light Source II

Meeting the critical scientific challenges of our energy future will require advanced new capabilities that a new facility called NSLS-II will uniquely provide. NSLS-II will be a new state-of-the-art, medium-energy electron storage ring (3 billion electron-volts) designed to deliver world-leading intensity and brightness, and will produce x-rays more than 10,000 times brighter than the current NSLS.

Research Highlights